1.A new drug is developed that blocks the transporter for
H+ secretion in gastric parietal cells. Which of the
following transport processes is being inhibited?
A. Simple diffusion
B. Facilitated diffusion
C. Primary active transport
D. Co transport
H+ secretion in gastric parietal cells. Which of the
following transport processes is being inhibited?
A. Simple diffusion
B. Facilitated diffusion
C. Primary active transport
D. Co transport
2.VitB12 and folic have the similar adverse effects,but
what separates one from the other?
A. Glossitis
B. No neurological symptoms in folic acid
C. muscle wasting
D. Dizziness
what separates one from the other?
A. Glossitis
B. No neurological symptoms in folic acid
C. muscle wasting
D. Dizziness
3.Absolute lymphocytosis with either hepatomegaly or
splenomegaly with or without lymphadenopathy is what
stage in CLL prognosis Scoring Rai staging system?
A. stage1
B. stage2
C. stage3
D. stage4
splenomegaly with or without lymphadenopathy is what
stage in CLL prognosis Scoring Rai staging system?
A. stage1
B. stage2
C. stage3
D. stage4
4.”gray line” of the eyelid is:
A. The mucocutaneous junction of the eyelid
margin
B. The location of the meibomian gland orifices
C. The muscle of Riolan
D. Posterior to the tarsus
A. The mucocutaneous junction of the eyelid
margin
B. The location of the meibomian gland orifices
C. The muscle of Riolan
D. Posterior to the tarsus
5.Which one of the following about Coats disease is true?
A. Usually bilateral
B. Associated with microphthalmia
C. Bimodal age distribution
D. Equally common between males and females
A. Usually bilateral
B. Associated with microphthalmia
C. Bimodal age distribution
D. Equally common between males and females
6Which cells projects to pial surface?
a. Axons of Betz cells
b. Martinotti cell
c. Fusiform cell
d. Stellate cell
a. Axons of Betz cells
b. Martinotti cell
c. Fusiform cell
d. Stellate cell
7Setting posture before planned move
ment:
a. Premotor cortex
b. Motor cortex
c. Frontal
d. Supplementary motor cortex
ment:
a. Premotor cortex
b. Motor cortex
c. Frontal
d. Supplementary motor cortex
8.Pyramids are formed by:
a. Arcuate nucleus
b. Vestibular nuclei
c. Interstitial cells of cajal
d. Lateral corticospinal tract
a. Arcuate nucleus
b. Vestibular nuclei
c. Interstitial cells of cajal
d. Lateral corticospinal tract
9.The inhibitory neurotransmitter in
CNS neurons is:
a. Glutamate
b. Aspartate
c. Gamma-amino butyric acid
d. Taurine
10.The hyperkinetic features of the Hun-
tington’s disease are due to the loss
of:
a. Nigrostriatal dopaminergic system
b. Intrastriatal cholinergic system
c. GABA-ergic and cholinergic system
d. Intrastriatal GABA-ergic and cholin-
ergic system
tington’s disease are due to the loss
of:
a. Nigrostriatal dopaminergic system
b. Intrastriatal cholinergic system
c. GABA-ergic and cholinergic system
d. Intrastriatal GABA-ergic and cholin-
ergic system
11.Which of the following statements is
true for excitatory postsynaptic poten-
tial (EPSP)?
a. Are self propagating
b. Shows all or none response
c. Arc proportional to the amount of
transmitter released by the presynap-
tic neuron
d. Are inhibitory at presynaptic termi-
nal
true for excitatory postsynaptic poten-
tial (EPSP)?
a. Are self propagating
b. Shows all or none response
c. Arc proportional to the amount of
transmitter released by the presynap-
tic neuron
d. Are inhibitory at presynaptic termi-
nal
12.Most righting reflex are integrated in
a) Motor cortex
b) spinal cord
c) Mid brain
d) Medulla
b) spinal cord
c) Mid brain
d) Medulla
13. Optical righting reflex is integrated in
A) cortex
B) spinal cord
C) Mid brain
D) Medulla
B) spinal cord
C) Mid brain
D) Medulla
14. Efferent from basal ganglia arise mainly from
A) striatum
B) subthalamic nucleus
C) Globus pallidus
D) Substantia nigra
B) subthalamic nucleus
C) Globus pallidus
D) Substantia nigra
15Which tract is ass. With distal limb muscle for skilled voluntary movement
A) Tectospinal
B) Reticulospinal
C) Rubrospinal
D) Vestibulospinal
B) Reticulospinal
C) Rubrospinal
D) Vestibulospinal
16. Term desynchronization indicate
A) S wave
B) Replacement of rhythmic wave with alpha wave
C) Replacement of rhythmic EEG pattern with low voltage, mixed frequency wave
D) All above
B) Replacement of rhythmic wave with alpha wave
C) Replacement of rhythmic EEG pattern with low voltage, mixed frequency wave
D) All above
17.The combination of alopecia & skin rash, painful peripheral neuropathy and confusion with lethargy are seen in?
A. Copper poisoning
B. Nickel poisoning
C. Selenium poisoning
D. Thallium poisoning
A. Copper poisoning
B. Nickel poisoning
C. Selenium poisoning
D. Thallium poisoning
Correct answer : D. Thallium poisoning
The combination of alopecia & skin rash, painful peripheral neuropathy and confusion with lethargy are known as ‘Thallium triad’.
It is indicative of chronic thallium poisoning.
Other symptoms include dystrophy of nails (Mees’ lines; also seen in arsenic poisoning), cardiovascular symptoms like hypertension and cardiomyopathy, ophthalmological symptoms like ptosis, ophthalmoplegia, nystagmus, keratitis, lens opacity and optic atrophy.
It is indicative of chronic thallium poisoning.
Other symptoms include dystrophy of nails (Mees’ lines; also seen in arsenic poisoning), cardiovascular symptoms like hypertension and cardiomyopathy, ophthalmological symptoms like ptosis, ophthalmoplegia, nystagmus, keratitis, lens opacity and optic atrophy.
18.A 45 year old farmer has itchy erythematous papular lesions on face, neck, ‘V‘ area of chest, dorsum of hands and forearms for 3 years. The lesions are more severe in summer and improve by 75% in winter. The most appropriate test to diagnose the condition would be:
A. Skin biopsy
B. Estimation of IgE levels in blood
C. Patch test
D. Intradermal prick test
A. Skin biopsy
B. Estimation of IgE levels in blood
C. Patch test
D. Intradermal prick test
Correct answer : C. Patch test
The history is suggestive of photodermatitis. Patch test is used for diagnosis of photodermatitis.
Patch test (photopatch test) : Here, 2 patches containing photosensitising material is applied on 2 different sites on the body. One of them is irradiated with UVA rays. The other is kept as control. Development of eczema is looked for upto 72 hours.
Analysis of results:
No development of eczema – patient does not have photodermatitis
Development of eczema under the patch irradiated with UVA – Photodermatitis
Development of eczema under both patches – Contact dermatitis
Development of eczema under the patch irradiated with UVA – Photodermatitis
Development of eczema under both patches – Contact dermatitis
19.Neoplastic dyskeratosis is seen in?
A. Darier’s disease
B. Warty dyskeratoma
C. Familial benign pemphigus
D. Actinic keratosis
A. Darier’s disease
B. Warty dyskeratoma
C. Familial benign pemphigus
D. Actinic keratosis
Correct answer : D. Actinic keratosis
Dyskeratosis is premature keratinisation of individual keratinocytes.
It can be benign or malignant.
Benign dyskeratosis is seen in Darier’s disease, Warty dyskeratoma and Familial benign pemphigus.
Neoplastic dyskeratosis is seen in Bowen’s disease, Squamous cell carcinoma and Actinic keratosis.
It can be benign or malignant.
Benign dyskeratosis is seen in Darier’s disease, Warty dyskeratoma and Familial benign pemphigus.
Neoplastic dyskeratosis is seen in Bowen’s disease, Squamous cell carcinoma and Actinic keratosis.
20.All of the following are seen in tuberous sclerosis except?
A. Civatte bodies
B. Koenen tumours
C. Ash leaf macules
D. Shagreen patch
A. Civatte bodies
B. Koenen tumours
C. Ash leaf macules
D. Shagreen patch
Correct answer : A. Civatte bodies
Civatte bodies are seen in lichen planus, which represent necrotic keratinocytes in dermis.
Ash leaf macules are the earliest cutaneous markers of tuberous sclerosis.
Koenen tumours are subungual fibromas.
Shagreen patches are collagen naevi usually seen on the lower back.
Ash leaf macules are the earliest cutaneous markers of tuberous sclerosis.
Koenen tumours are subungual fibromas.
Shagreen patches are collagen naevi usually seen on the lower back.
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